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Prof. dr. A.P. (Annemarie) van Wezel

Professor of Environmental Ecology
Faculty of Science
Institute for Biodiversity and Ecosystem Dynamics
Photographer: Dirk Gillissen

Visiting address
  • Science Park 904
  • Room number: C4.218
Postal address
  • Postbus 94240
    1090 GE Amsterdam
  • Curriculum Vitae

    Prof. Annemarie van Wezel (1968, MSc Biology UU, PhD environmental chemistry and toxicology UU) has long experience as scientist in water quality, risk assessment and mitigation, environmental toxicology and chemistry, and environmental policy evaluation. She was granted as applicant and co-applicant many projects in the field of chemicals of emerging concern and water quality, examples are the European projects FP7 Solutions, ITN ECORISK2050, ITN PERFORCE3, and Dutch NWO funded projects such as Shale gas & water, TRAMP (Technologies for risk assessment for microplastics), EMERCHE (Effect-directed Monitoring tools to assess Ecological and human health Risks of CHemicals of Emerging concern in the water cycle), RUST (Re-USe of Treated effluent for agriculture), PsychoPharmac’eau (Psychopharmaceutical Prevention & Pilots to Reduce Effects in the water cycle), NWO Large Scientific Infrastructure; Authorative and Rapid Identification System for Essential biodiversity information (ARISE) and NWO Perspective AQUACONNECT. She is interested in the science-to-policy interface, in scientific outreach and has ample experience in media appearances. She is a member of the Dutch Health Council and the Dutch Board on authorization of plant protection products and biocides CTGB. She holds the chair Environmental Ecology and is Scientific Director of IBED (Institute for Biodiversity and Ecosystem Dynamics) at the University of Amsterdam.

  • Additional functions
    • 2020-current: Chair Science Committee Netherlands Institute of Ecology (NIOO-KNAW)
    • 2020-current: Member Board of Associates (BoA) Institute for Advanced Study (IAS) (UvA)
    • 2020-current: Member of the Permanent Committee Large-scale Scientific Infrastructure (NWO)
    • 2019-current: Advisor to Board NDFF (Nederlandse Database Flora en Fauna)

    • 2019-current: Board member Netherlands Ecological Research Network NERN

    • 2019-current: Associate editor ‘Frontiers in Environmental Science: Toxicology, Pollution and the Environment

    • 2017-current Member Stichting International Water Conferences

    • 2016-current Member Dutch Health Council, Member Committee Signals Health and Environment

    • 2014-current Member of the Dutch board on Authorization of Plant Protection Products and Biocides (CTGB)

    • 2014-current Member board Postdoctoral Education on Toxicology

    • 2014-current Member Editorial Board 'Reviews of Environmental Contamination and Toxicology' (Springer)
  • Projects
  • Publications






    • Brack, W., Dulio, V., Ågerstrand, M., Allan, I., Altenburger, R., Brinkmann, M., ... Vrana, B. (2017). Towards the review of the European Union Water Framework management of chemical contamination in European surface water resources. Science of the Total Environment, 576, 720-737.
    • Butkovskyi, A., Bruning, H., Kools, S. A. E., Rijnaarts, H. H. M., & van Wezel, A. P. (2017). Organic Pollutants in Shale Gas Flowback and Produced Waters: Identification, Potential Ecological Impact, and Implications for Treatment Strategies. Environmental Science and Technology, 51(9), 4740-4754.
    • Bäuerlein, P. S., Emke, E., Tromp, P., Hofman, J. A. M. H., Carboni, A., Schooneman, F., ... van Wezel, A. P. (2017). Is there evidence for man-made nanoparticles in the Dutch environment? Science of the Total Environment, 576, 273-283. [details]
    • Fischer, A., Ter Laak, T., Bronders, J., Desmet, N., Christoffels, E., van Wezel, A., & van der Hoek, J. P. (2017). Decision support for water quality management of contaminants of emerging concern. Journal of Environmental Management, 193, 360-372.
    • Koelmans, A. A., Besseling, E., Foekema, E., Kooi, M., Mintenig, S., Ossendorp, B. C., ... Scheffer, M. (2017). Risks of Plastic Debris: Unravelling Fact, Opinion, Perception, and Belief. Environmental Science and Technology, 51(20), 11513-11519.
    • Munthe, J., Brorström-Lundén, E., Rahmberg, M., Posthuma, L., Altenburger, R., Brack, W., ... van Wezel, A. (2017). An expanded conceptual framework for solution-focused management of chemical pollution in European waters. Environmental Sciences Europe, 29(1).
    • Van Wezel, A. P., Ter Laak, T. L., Fischer, A., Bäuerlein, P. S., Munthe, J., & Posthuma, L. (2017). Mitigation options for chemicals of emerging concern in surface waters operationalising solutions-focused risk assessment. Environmental Science: Water Research & Technology, 3, 403-414.


    • Sjerps, R. M. A., Vughs, D., van Leerdam, J. A., ter Laak, T. L., & van Wezel, A. P. (2016). Data-driven prioritization of chemicals for various water types using suspect screening LC-HRMS. Water Research, 93, 254-264.
    • van Wezel, A., Caris, I., & Kools, S. (2016). Release of primary microplastics from consumer products to wastewater in The Netherlands. Environmental Toxicology and Chemistry, 35(7), 1627-1631.


    • Brack, W., Altenburger, R., Schüürmann, G., Krauss, M., López Herráez, D., van Gils, J., ... de Aragão Umbuzeiro, G. (2015). The SOLUTIONS project. Science of the Total Environment, 503-504, 22-31.
    • Coppens, L. J. C., van Gils, J. A. G., Ter Laak, T. L., Raterman, B. W., & van Wezel, A. P. (2015). Towards spatially smart abatement of human pharmaceuticals in surface waters. Water Research, 81, 356-365.
    • Kolkman, A., Martijn, B. J., Vughs, D., Baken, K. A., & van Wezel, A. P. (2015). Tracing Nitrogenous Disinfection Byproducts after Medium Pressure UV Water Treatment by Stable Isotope Labeling and High Resolution Mass Spectrometry. Environmental Science and Technology, 49, 4458-4465.


    • Kettler, K., Veltman, K., van de Meent, D., van Wezel, A., & Hendriks, A. J. (2014). Cellular uptake of nanoparticles as determined by particle properties, experimental conditions, and cell type. Environmental Toxicology and Chemistry, 33(3), 481-492.


    • Brand, W., de Jongh, C. M., Linden, S. C., Mennes, W., Puijker, L. M., van Leeuwen, C. J., ... Heringa, M. B. (2013). Trigger values for investigation of hormonal activity in drinking water and its sources using CALUX bioassays. Environment International, 55(May 2013), 109-118.
    • Kolkman, A., Emke, E., Bäuerlein, P. S., Carboni, A., Tran, D. T., ter Laak, T. L., ... de Voogt, P. (2013). Analysis of (functionalized) fullerenes in water samples by liquid chromatography coupled to high-resolution mass spectrometry. Analytical Chemistry, 85(12), 5867-5874. [details]
    • Punt, A., Brand, W., Murk, A. J., van Wezel, A., Schriks, M., & Heringa, M. B. (2013). Effect of combining in vitro estrogenicity data with kinetic characteristics of estrogenic compounds on the in vivo predictive value. Toxicology in Vitro, 27(1), 44-51.


    • ter Laak, T. L., Puijker, L. M., van Leerdam, J. A., Raat, K. J., Kolkman, A., de Voogt, P., & van Wezel, A. P. (2012). Broad target chemical screening approach used as tool for rapid assessment of groundwater quality. Science of the Total Environment, 427/428, 308-313. [details]


    • McCarty, L. S., Landrum, P. F., Luoma, S. N., Meador, J. P., Merten, A. A., Shephard, B. K., & van Wezel, A. P. (2011). Advancing environmental toxicology through chemical dosimetry: external exposures versus tissue residues. Integrated Environmental Assessment and Management, 7(1), 7-27.
    • Schriks, M., Heringa, M. B., de Voogt, P., & van Wezel, A. P. (2011). Response to Mario Schirmer, Marion Martienssen and Kristin Schirmer’s comments regarding "Toxicological relevance of emerging contaminants for drinking water quality" by Schriks et al. Water Research, 45(3), 1515-1517. [details]
    • Van Wezel, A. P., Morinière, V., Emke, E., ter Laak, T., & Hogenboom, A. C. (2011). Quantifying summed fullerene nC60and related transformation products in water using LC LTQ Orbitrap MS and application to environmental samples. Environment International, 37(6), 1063-1067.
    • Woutersen, M., Belkin, S., Brouwer, B., Van Wezel, A. P., & Heringa, M. B. (2011). Are luminescent bacteria suitable for online detection and monitoring of toxic compounds in drinking water and its sources? Fresenius Zeitschrift fur Analytische Chemie, 400(4), 915-929.


    • Schriks, M., Heringa, M. B., van der Kooij, M. M. E., de Voogt, P., & van Wezel, A. P. (2010). Toxicological relevance of emerging contaminants for drinking water quality. Water Research, 44(2), 461-476. [details]
    • Schriks, M., van Leerdam, J. A., van der Linden, S. C., van der Burg, B., van Wezel, A. P., & de Voogt, P. (2010). High-resolution mass spectrometric identification and quantification of glucocorticoid compounds in various wastewaters in the Netherlands. Environmental Science and Technology, 44(12), 4766-4774. [details]
    • Van Wezel, A., Mons, M., & Van Delft, W. (2010). New methods to monitor emerging chemicals in the drinking water production chain. Journal of Environmental Monitoring, 12(1), 80-89.
    • ter Laak, T. L., van der Aa, M., Houtman, C. J., Stoks, P. G., & van Wezel, A. P. (2010). Relating environmental concentrations of pharmaceuticals to consumption: A mass balance approach for the river Rhine. Environment International, 36(5), 403-409.



    • van Wezel, A. P., Franken, R. O. G., Drissen, E., Versluijs, K. C. W., & van den Berg, R. (2008). Societal cost-benefit analysis for soil remediation in The Netherlands. Integrated Environmental Assessment and Management, 4(1), 61-74.




    • Moermond, C. T. A., Tijink, J., Van Wezel, A. P., & Koelmans, A. A. (2001). Distribution, speciation, and bioavailability of lanthanides in the Rhine-Meuse estuary, the Netherlands. Environmental Toxicology and Chemistry, 20(9), 1916-1926.


    • Roex, E. W. M., Van Gestel, C. A. M., Van Wezel, A. P., & Van Straalen, N. M. (2000). Ratios between acute aquatic toxicity and effects on population growth rates in relation to toxicant mode of action. Environmental Toxicology and Chemistry, 19(3), 685-693.
    • Van Wezel, A. P., Van Vlaardingen, P., Posthumus, R., Crommentuijn, G. H., & Sijm, D. T. H. M. (2000). Environmental risk limits for two phthalates, with special emphasis on endocrine disruptive properties. Ecotoxicology and Environmental Safety, 46(3), 305-321.


    • Ciarelli, S., Van Straalen, N. M., Klap, V. A., & Van Wezel, A. P. (1999). Effects of sediment bioturbation by the estuarine amphipod Corophium volutator on fluoranthene resuspension and transfer into the mussel (Mytilus edulis). Environmental Toxicology and Chemistry, 18(2), 318-328.
    • Sanderson, J. T., Commandeur, J. N. M., Van Wezel, A., & Vermeulen, N. P. E. (1999). Bioassays for the detection of chemicals that can form bioactivation- dependent reactive free radicals. Environmental Toxicology and Chemistry, 18(6), 1236-1243.


    • Van Wezel, A. P., & Jonker, M. T. O. (1998). Use of the lethal body burden in the risk quantification of field sediments; Influence of temperature and salinity. Aquatic Toxicology, 42(4), 287-300.


    • De Gert-Jan Maagd, P., Van De Klundert, I. C. M., Van Wezel, A. P., Opperhuizen, A., & Sijm, D. T. H. M. (1997). Lipid content and time-to-death-dependent lethal body burdens of naphthalene and 1,2,4-trichlorobenzene in fathead minnow (Pimephales promelas). Ecotoxicology and Environmental Safety, 38(3), 232-237.
    • Van Wezel, A. P., Schmitz, M. G. J., & Tielens, A. G. M. (1997). Acetylcholinesterase and ATPase activities in erythrocyte ghosts are not affected by 1,2,4-trichlorobenzene: Implications for toxicity by narcotic chemicals. Environmental Toxicology and Chemistry, 16(11), 2347-2352.


    • Van Wezel, A. P., Cornelissen, G., Van Kees Miltenburg, J., & Opperhuizen, A. (1996). Membrane burdens of chlorinated benzenes lower the main phase transition temperature in dipalmitoyl-phosphatidylcholine vesicles: Implications for toxicity by narcotic chemicals. Environmental Toxicology and Chemistry, 15(2), 203-212.
    • Van Wezel, A. P., De Vries, D. A. M., Sijm, D. T. H. M., & Opperhuizen, A. (1996). Use of the lethal body burden in the evaluation of mixture toxicity. Ecotoxicology and Environmental Safety, 35(3), 236-241.


    • Van Wezel, A. P., & Opperhuizen, A. (1995). Narcosis due to environmental pollutants in aquatic organisms: Residue-based toxicity, mechanisms, and membrane burdens. Critical Reviews in Toxicology, 25(3), 255-279.
    • Van Wezel, A. P., & Opperhuizen, A. (1995). Thermodynamics of partitioning of a series of chlorobenzenes to fish storage lipids, in comparison to partitioning to phospholipids. Chemosphere, 31(7), 3605-3615.
    • Van Wezel, A. P., De Vries, D. A. M., Kostense, S., Sijm, D. T. H. M., & Opperhuizen, A. (1995). Intraspecies variation in lethal body burdens of narcotic compounds. Aquatic Toxicology, 33(3-4), 325-342.
    • Van Wezel, A. P., Punte, S. S., & Opperhuizen, A. (1995). Lethal body burdens of polar narcotics: Chlorophenols. Environmental Toxicology and Chemistry, 14(9), 1579-1585.
    • Van Wezel, A. P., Sijm, D. T. H. M., Seinen, W., & Opperhuizen, A. (1995). Use of lethal body burdens to indicate species differences in susceptibility to narcotic toxicants. Chemosphere, 31(5), 3201-3209.


    • Rietjens, I. M. C. M., Schriks, M., Houtman, C. J., Dingemans, M. M. L., & van Wezel, A. P. (2022). Letter to the Editor on Bil et al. 2021 “Risk Assessment of Per- and Polyfluoroalkyl Substance Mixtures: A Relative Potency Factor Approach”. Environmental Toxicology and Chemistry, 41(1), 7-12.


    • van Wezel, A. (2019). Chemophilia/Chemophobia. (Oratiereeks; No. 613). Amsterdam: Universiteit van Amsterdam. [details]


    • de Voogt, P., Puijker, L., Vink, C., & van Wezel, A. (2009). Smaak- en geurdrempels van benzine-additieven en voorkomen in waterwingebieden. H2O, 42(25/26), 46-47. [details]


    • Emke, E., Kolkman, A., Carboni, A., van Wezel, A. P., & de Voogt, P. (2012). Determination of functionalized engineered carbon nanoparticles in environmental samples by HPLC-UV/LTQ-ORBITRAP MS. 423. Abstract from 6th SETAC World Congress/SETAC Europe 22nd Annual Meeting, Berlin, Germany, May 2012, .
    • Krystek, P., Spallek, M. J., Bäuerlein, P. S., Kooij, P., de Voogt, P., & van Wezel, A. (2012). Pilot study about the identification of nanoparticles in mouthwashes by asymmetric flow field flow fractionation (AF4) with selected detection. Paper presented at NanonextNL RATA, .


    • Schriks, M., Heringa, M. B., van der Kooi, M. M. E., de Voogt, P., & van Wezel, A. P. (2010). Toxicological relevance of emerging contaminants for drinking water quality. Abstract from IWA Conference, Singapore, June 2010, . [details]
    • Schriks, M., Heringa, M. B., van der Kooij, M. M. E., de Voogt, P., & van Wezel, A. P. (2010). Toxicological relevance of emerging contaminants for drinking water quality. Abstract from SETAC Europe Annual Meeting, Seville, . [details]

    Media appearance

    • van Wezel, A. (01-02-2020). Chemophilia/Chemophobia [Print] Bodem. Chemophilia/Chemophobia.

    Journal editor

    • van Wezel, A. (editor) (2019-). Frontiers in Environmental Science (Journal).
    • van Wezel, A. (editor) (2014-). Reviews of Environmental Contamination and Toxicology (Journal).


    • van Dijk, J., Gustavsson, M., Dekker, S. & van Wezel, A. (1-10-2020). Data for: "Towards ‘One Substance – One Assessment’: an Analysis of EU Chemical Registration and Aquatic Risk Assessment Frameworks. Mendeley Data.
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  • Ancillary activities
    • CTGB
    • Gezondheidsraad
    • SCHEER
    • SAPEA
    • Springer
      Editor Reviews of Environmental Contamination and Toxicology
    • St. International Water Conference
    • Postgraduate Education Toxicology
      Advisering en Toezicht Supervisory Board